4-amino-3-phenylbutyric acid:

• GABA derivative that crosses the blood-brain barrier and acts as a GABA-B agonist1, 2 
• GABA is important for calm3 and sleep4

Zembrin ® (Sceletium tortuosum extract):

• Herbal extract that is a dual inhibitor of phosphodiesterase-4 (PDE-4) and serotonin transporters5
• A randomized, double-blind, placebo-controlled study found Zembrin significantly improved onset of sleep and multiple cognitive functions6 
• Subjects taking Zembrin reported "higher spirits" and "better coping with stress and low mood"7
• Effects of Zembrin have been shown to impact brain activity after one dose8

Blueberry fruit extract (standardized to 12% anthocyanins):

• Anthocyanins are flavonoids with strong antioxidant properties that have been shown to increase levels of brain-derived neurotrophic factor (BDNF)9, 10 
• BDNF plays a critical role in modulating neuron function11