Curcumin is the active compound in turmeric, an orange-colored spice used for thousands of years in cooking and medicine. Curcumin has been shown to have strong NFkB-modulating properties and plays a crucial role in maintaining normal inflammatory balance. Studies have shown that curcumin specifically maintains normal inflammatory balance in the most significant GI challenges.
Green Tea Extract (EGCg)
Green tea, used for centuries as a health tonic, is a potent antioxidant and is effective for maintaining normal inflammatory balance. Its most researched active component, EGCg, has been repeatedly shown to protect against free radical damage and balance markers of inflammation.
Larch arabinogalactan is a fermentable polysaccharide fiber from the larch tree that promotes optimal immune health by supporting the growth of beneficial gut flora and strengthening the activity of NK cells.
Skullcap Root Extract
This popular Chinese botanical has been shown to maintain normal inflammatory balance and support cardiovascular health. Skullcap possesses potent antioxidant properties. Research has shown it attenuates NFkB and inhibits COX-2 expression.
A flavonoid found in a variety of botanicals, vegetables and fruits, quercetin is a potent antioxidant that inhibits inducible ICAM-1 expression, an important pathway for maintaining normal inflammatory balance. It has also been shown to enhance epithelial barrier function in the intestines by stabilizing mast cells through the release of cell-protective factors.
Amino acid glycine is essential for healthy gut mucosa and normal tissue repair. Numerous studies have shown these amino acids to be soothing to the GI lining. Recent research also highlights the synergistic role between amino acids and a healthy balance of probiotic bacteria in the GI tract.
One of the key functions of vitamin D is its ability to tighten gap junctions in the intestinal lining to create a strong barrier that protects the body from foreign substances. Recent research suggests that improving vitamin D status significantly affects the expression of genetic pathways linked to immune activity. Vitamin D up-regulates specific genes that increase cellular production of natural compounds that protect us against pathogens. Higher blood levels of vitamin D have been shown to enhance immune function and soothe tissues of the GI tract.