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Thorne Research, Hepagen-Fc - Hepatic Support - 60 Capsules

  • $32.00
  • $29.00

Hepatic support for cats and small dogs

  • protects hepatic cells
  • supports normal phase I and II detoxification processes
  • supports healthy glutathione levels

Because toxic components increasingly find their way into food, water, and the environment, the liver can be a very busy organ for companion animals. Hepagen-Fc provides a unique combination of the beneficial liver herbs milk thistle and curcumin (from turmeric), with antioxidants and important ingredients that support the liver's normal phase I and phase II detoxification processes. Hepagen-Fc contains the curcumin phytosome, CurcuVET®, a unique, well-absorbed curcumin/phosphatidylcholine complex.

Whether taken from food or as a supplement, curcumin is generally poorly absorbed into the bloodstream. Indena S.p.A., the worldwide experts in botanical extract technology, has uncovered the key to curcumin absorption – phytosome technology. CurcuVET is Indena’s unique curcumin extract that is significantly better absorbed than other curcumin extracts. The beneficial effects of curcumin may be due to the fact that, in addition to being an antioxidant, it can help maintain the animal's normal inflammatory response in the liver.

Silybum marianum (milk thistle) contains several flavonolignans, the most biologically active of which is silybin. The antioxidant activity of silybin appears to stabilize hepatocyte membranes, neutralize free radicals, and maintain the liver's glutathione levels. Hepagen-Fc contains silybin in the form of a well-absorbed phytosome bound to phosphatidylcholine (Siliphos).

The phosphatidylcholine content of CurcuVET and Siliphos – in addition to enhancing the absorption of these important hepatoprotective flavonoids – also provides liver support in its own right. Phosphatidylcholine is the most significant phospholipid in hepatic cell membranes. It helps regulate the gallbladder and is used extensively in the liver to move fats in and out of cells.

Pyridoxal 5'-phosphate acts as a cofactor for enzymes, catalyzes reactions with amino acids, and aids in the synthesis of non-essential amino acids. In this formula, the active form of vitamin B6, pyridoxal 5'-phosphate, is provided because healthy liver function is necessary for activation of vitamin B6. Vitamin B12 is required for proper digestion and absorption of food and is provided in one of its active coenzyme forms – methylcobalamin.

Dimethylglycine (DMG) is a derivative of glycine, the simplest amino acid. It is a building block for many important substances, including methionine and choline. Methionine is an essential sulfur-containing amino acid necessary for phase II detoxification. It helps metabolize fats and is a precursor to cysteine and taurine synthesis. It can be converted to cysteine, a component of glutathione, an important endogenous antioxidant.

N-acetylcysteine (NAC) is composed of the amino acid cysteine and a sulfhydryl group, enabling it to interact with disulfide bonds. NAC serves as a precursor for the synthesis of glutathione.

Inositol is an important lipotropic factor – a substance that helps the liver metabolize fats

Suggested Use

Cats: 2 capsules daily
 Dogs: 1 capsule per 10 lbs body weight twice daily


Active Ingredients per Capsule:
L-Methionine 22.5 mg.
N-Acetyl-L-Cysteine 22.5 mg.
Dimethylglycine (Hydrochloride) 11.3 mg.
Inositol 11.3 mg.
Milk Thistle Phytosome* (Silybum marianum extract (fruit) / Phosphatidylcholine complex) (Siliphos) 11.3 mg.
Curcumin Phytosome* (Curcuma longa extract (root) / Phosphatidylcholine complex) (CurcuVET) 11.3 mg.
Pyridoxal 5'-Phosphate (Vitamin B6) 1.3 mg.
Methylcobalamin (Vitamin B12) 12.5 mcg.

Other Ingredients: Hypromellose (derived from cellulose) capsule, Leucine, Cellulose, Alaska Pollock (dried skins) (Theragra chalcogramma), Silicon Dioxide.

*This product uses Indena S.p.A.'s curcumin phytosome (CurcuVET®) and silybin phytosome (Siliphos). CurcuVET and Siliphos are registered trademarks of Indena S.p.A.


For use in cats and small dogs only.

Recommended for hepatic support.

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